Whole Genome Sequencing and the New Genomics Wave
Recent advances in DNA sequencing technology have reduced costs to the point that middle-class Americans can now afford to obtain and analyze their personal genome sequences on their own. Consumer genomics companies advertise that they can reveal not only disease-related mutations but also benign traits or likely ancestry – direct-to-consumer marketing is similar to marketing […]
Read MoreWave Genome Germany
Wave Genome Germany (WGG) is a network of German laboratories that send sequenced specimens directly to RKI for whole genome sequencing, in order to generate an unbiased sample set that detects emerging variants and allows comparative analysis. Molecular phylogeny and Nextstrain-based mutation events indicate that during the transition from wave 1 to wave 2, several […]
Read MoreThe Wave Genome Movie Review
Based on real events, this movie follows an experiment at Gordon High that spirals out of control into an oppressive cult. Although genome sequencing has revolutionized medicine by linking diseases to specific genes and offering at-home genetic tests, it has also created new forms of inequality and misinformation – issues we explore this month on […]
Read MoreWave Genetics and GSK Are Collaborating on Oligonucleotide Programs
Wave and GSK are working in partnership on several oligonucleotide programs for treating multiple diseases, including Hepatitis B, Fatty Liver Disease (NAFLD) and AAT Diseases. Among them is Bepirovirsen – an antisense oligonucleotide entering Phase III for Hepatitis B treatment; WVE-006 an RNA Editing Program targeting AAT Disease; bepirovirsen, an antisense antisense oligonucleotide that will […]
Read MoreWave Oligonucleotides – A Revolutionary Idea That Could Transform Medical Research
Wave oligonucleotides are synthetic small RNA-targeting molecules designed to reduce, restore or modulate levels of RNA. When included into gene therapies for treating disease they provide effective therapies. Scientists from UT Southwestern have successfully utilized electromagnetic waves to induce insulin production in mice, opening the door for potential new therapies for diabetes based on an […]
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