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Information Wellness Blog

Detailed Reviews and Guides about energy and informational health and wellness

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July 18, 2024|Editorial

Quantum Magnetic Resonance Therapy for Osteoarthritis

A computer controlled device has developed to produce precise quantum electromagnetic beams that alter membrane potential of diseased cells and tissues, offering effective relief to patients suffering from various conditions.

QMR technology effectively blocks LPS/HA-activation of the NLRP3 inflammasome and decreases COX-2, iNOS, and IL-1b protein expression and secretion in macrophage THP-1 cells.

Inflammation

MR technology’s fundamental principles rely on magnetic resonance, a quantum mechanical effect caused when an exposed quantum system interacts with an electromagnetic field. Magnetic interactions among particles within this quantum system cause electromagnetic waves within it to vibrate in response, creating a vibration within an electromagnetic wave which has no classical equivalent but instead can be measured with electronic equipment.

Vibrations of electromagnetic waves can also be used to detect changes in physical quantities such as temperature or pressure in a system, using electronic methods like EPR (electron paramagnetic resonance) or nuclear magnetic resonance (NMR). This principle resembles Larmor precession of electrons within an atom without energy exchange between particles; instead it relies on magnetic interactions induced by unpaired electron spin angular momentum that exists across matter – something Larmor precession cannot.

QMR therapy may reduce inflammation by stimulating cell production of ATP – an essential energy molecule involved in many cell processes such as stress responses and inflammation reactions. QMR therapies may increase production by improving mitochondrial function or increasing oxidative phosphorylation.

Recent research has demonstrated how QMR treatment effectively restrains LPS/HA-induced activation of the NLRP3 inflammasome in THP-1 differentiated macrophage cells by blocking COX-2 and iNOS protein expression, as well as decreasing NF-kB activity and peroxynitrite levels. Furthermore, QMR treatment significantly decreased secretion of proinflammatory cytokines such as IL-18 and IL-1b by LPS/HA treated macrophages.

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Though the results of this study were encouraging, researchers only focused on a limited set of inflammatory markers and pathways. Future research should explore more anti-inflammatory stimuli and cell types to further comprehend QMR therapy’s anti-inflammatory benefits; but it remains clear that this innovative treatment could prove helpful in both the prevention and treatment of osteoarthritis (OA).

Pain

Quantum magnetic resonance therapy (QMRT) is an effective anti-inflammatory that can significantly ease pain associated with osteoarthritis (OA). QMRT works through interactions between electromagnetic fields and water molecules in cells; the latter serve to transmit electromagnetic signals while at the same time acting as carriers for other substances, including drugs or hormones.

RFQMR beams can generate voltage potentials that force hydrogen protons into tissue’s extracellular matrix, stimulating chondrocytes to secrete lubricating fluid that enhances joint elasticity and hydration – helping relieve pain considerably. Furthermore, electromagnets in these devices emit low-frequency electromagnetic fields which stimulate nerves into producing natural painkillers such as endorphins.

One study reported on a patient suffering from an anaplastic astrocytoma who saw considerable improvements after receiving four weeks of quantum magnetic resonance therapy for this condition. His tumor shrunk, no longer appearing on MRI scans and allowed him to move his head and neck without discomfort while speaking clearly without discomfort despite previous surgery and chemotherapy treatments. The treatment proved successful despite prior attempts.

This research marks the first demonstration that quantum magnetic resonance technology (QMR) can directly modify macrophage polarization toward anti-inflammatory M2 phenotype in living tissue in real time, supporting the theory that QMR can act as an adjunctive therapy against inflammation-related diseases by targeting cell polarization.

A patented device known as the Cytotron delivers rotating, target-specific radio frequencies at safe frequencies that penetrate deep into tissues and cells of the body. These frequencies are much lower than those found in cell phones or microwave ovens and therefore allow deeper penetration.

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This device uses advanced electronic equipment to collect the weak magnetic field generated by an individual’s body, then analyzes this data. Using this information, doctors can assess their health status and any main problems they are having while also offering standard preventative advice. Based on quantum medicine principles – an emerging high-tech field combining medical science, bioinformatics, and electronic engineering.

Bone Remodeling

Electromagnetic fields have the power to change the structures and functions of cells and tissues in ways that have far-reaching implications for health. Pulsed magnetic fields, for instance, can quickly restart bone fracture healing that had become resistant. PEMF therapy, in turn, has been found to relieve osteoarthritis pain effectively while those same frequencies can also be found used by Reiki therapists for producing electromagnetic fields with optimal frequency ranges for stimulating tissue and bone healing.

RFQMR is an advanced technology that uses complex electromagnetic beam patterns in the sub-radio and near radio frequency spectrum, to precisely target tissues such as bones and cartilage with complex quantum electromagnetic beam patterns. By altering QMR spin in hydrogen atoms, this creates a streaming voltage potential flow through joints by forcing protons through extracellular matrix due to altered quantum magnetic resonance spin properties in them; stimulating chondrocytes located there.

This process, similar to how gravity and acceleration stress bones in knees to promote bone growth, can reduce arthritic inflammation by modulating its response and also slow the progression of osteoarthritis by encouraging cartilage production while slowing its degradation.

Arthritic symptoms arise due to energy being depleted from bones and cartilage structures, typically as the result of disrupted water-electromagnetism resonance systems; specifically these resonance systems are blocked by electromagnetic fields generated by Earth, its satellites and Schumann resonance; when someone ventures beyond earth orbit and loses this natural resonance it depletes massive amounts of energy across bones, organs and other tissues at an alarmingly rapid rate.

Robert Becker demonstrated through extensive experiments conducted during the 1950’s that bones contain an intrinsic electron current which allows their regeneration. He discovered this current made proteins which make up bone align properly while simultaneously stimulating calcium deposits into it to strengthen it further. Furthermore, this piezoelectric current was powered by semiconduction which then allowed bones to regenerate themselves.

Anti-Inflammatory Effects

Inflammation plays an essential role in osteoarthritis, the leading cause of pain and disability among older adults. While traditional treatments have shown little efficacy for this condition, often leaving many patients only one option available: joint replacement surgery. QMR therapy has the potential to dramatically enhance quality of life for such patients by targeting sources of inflammation directly as well as initiating healing processes that could alleviate symptoms.

Rotational Field Quantum Magnetic Resonance (RFQMR) is a non-ionising and non-thermal quantum electromagnetic beam pattern which has been shown to modulate cell membrane potential and downstream signaling in an accurate manner, and induce regenerative processes in knee cartilage articular cartilage.

Cytotron, a patented computer-controlled device capable of emitting RFQMR beams at any desired site in the body, enables doctors to target RFQMR beams at specific areas in need. Generated using 96 specially designed Mn-Pb-Cu guns, they have been shown to alter ionic and electronic properties within cells which ultimately change selective permeability.

Published recently are the findings from an in vitro study evaluating the effect of RFQMR on human macrophage THP-1 cells. According to this in vitro research study, QMR exposure decreased expression and secretion of proinflammatory mediators such as IL-1, IL-18 and TNF-, as well as inhibited activation of the NLRP3 inflammasome in these cells. Additionally, exposure increased ATP production while decreasing levels of oxidative stress within these cells.

This work represents a vital step towards understanding how biophysical vulnerabilities of solid tumors can be exploited to effectively treat and palliate cancer. Targeting biological signals without altering normal tissue function is key to moving beyond chemotherapy-based cancer treatments and increasing overall survival for terminally ill cancer patients. This approach to cancer care is founded on the idea that cancer cells rely heavily on biophysical signals produced by gravitational, thermal, chemical and mechanical stresses; by exploiting these vulnerabilities with innovative therapies such as QMRT it should become possible to create more effective cancer therapies.

July 18, 2024|Editorial

Frequency Specific Microcurrent Therapy

Frequency specific microcurrent (FSM) therapy is a noninvasive, painless technique using low-level electric currents that encourage healthy cell functioning, increasing production of ATP while simultaneously decreasing inflammation and scar tissue formation.

FSM can be extremely effective at treating nerve, muscle and joint pain as well as dissolving or softening scar tissue. Furthermore, FSM supports healing after trauma as well as in cases of fibromyalgia.

It’s Non-Invasive

FSM is a non-invasive, painless treatment designed to work alongside your body’s natural healing processes. Utilizing pairs of frequencies, low-level microcurrent amperage currents and biologic resonance principles, FSM uses iterations frequency cycles in conjunction with biological resonance principles to effectively address pathological conditions.

FSM utilizes frequency therapy to restore proper cell functioning that has been disturbed due to disease or injury, helping restore proper cellular functions that have become disrupted as a result. The frequency therapy works to restore cell-by-cell communication pathways between individual tissues within our bodies and works effectively towards this end.

Frequencies used in FSM can be applied through various conductors on the body (conductive graphite gloves, gel electrode patches or hands wrapped in moistened cloth). Once one or more frequencies have been applied to an area being treated, patients often feel an alteration to skin softness – although not at superficial layers like epidermis – such as deeper skeletal muscles being addressed by FSM treatments.

Once frequencies are applied to tissues, cells respond by breaking down adenosine triphosphate (ATP), an energy source used by your body for healing. This boost in energy also accelerates protein production rates, enhances communication among cells more effectively and supports waste removal from them.

FSM is particularly effective at treating fibromyalgia and other chronic conditions that have not responded to other methods of manual therapy or medications, including managing chronic pain associated with this disorder and helping patients live life more fully.

If you are considering adding FSM into your treatment plan, we advise seeking out a practitioner with extensive knowledge in FSM protocols as well as any additional therapeutic modalities you are currently employing. It is also wise to be familiar with any possible risks or contraindications of FSM before making an informed decision as to whether this technique suits you personally.

It’s Safe

Frequency Specific Microcurrent (FSM) treatment employs frequencies that mimic those used by your body to heal itself. They are transmitted using a small two-channel device and applied directly to specific areas on the body – although most patients do not detect their microcurrents at all! FSM frequencies combine and deliver sequences designed to address specific medical conditions diagnosed.

FSM therapy utilizes frequency combinations that can reduce inflammation and stimulate new cell and tissue growth, making it particularly useful in healing damaged muscles, joints, ligaments and tendons. Furthermore, FSM can enhance nerve function and alleviate any associated nerve pain.

Inflammation is an instinctive response to injury and illness, yet chronic inflammation can have detrimental effects on health. FSM therapy may reduce this response by activating anti-inflammatory molecules to counter pro-inflammatory cytokines released during inflammation; this treatment could prove useful in relieving symptoms associated with arthritis, tendonitis, fibromyalgia, frozen shoulder and carpal tunnel syndrome.

FSM for treating damaged tissue can increase electrical conductivity in an injured area, helping accelerate healing. Furthermore, FSM has also been proven to boost cell energy and production of Adenosine Triphosphate which accelerates recovery times after accidents or surgeries. Finally, its use has also shown to significantly shorten healing time periods following such trauma.

FSM frequencies can help muscles, tendons and nerves regain their electrical conductivity by breaking down and eliminating scar tissue or adhesions that have formed, making FSM especially helpful in treating tennis elbow or frozen shoulder conditions.

Before initiating an FSM treatment regimen, it is crucial to obtain an accurate diagnosis. If you experience shoulder pain, for instance, it is critical to know whether it stems from muscles, tendons, bursae, discs or nerves – treating an incorrect source may fail to bring relief.

Certain people should avoid FSM treatments, including those who have pacemakers, implanted pumps, uncontrolled seizures or are pregnant. A licensed chiropractor can help determine whether FSM would be appropriate in your case.

It’s Effective

Frequency specific microcurrent therapy (FSM) uses only small amounts of electrical energy – equivalent to that produced naturally by your body – which are applied directly through an ampere (which measures your electrical current output). FSM treatments are safe for most people and do not hurt, although some may experience slight vibration sensation during treatment sessions.

Microcurrent therapy employs different frequencies of energy applied sequentially to different parts of the body to create resonance effects in tissues and conditions to alleviate symptoms and promote health. Studies have demonstrated how microcurrent can increase cellular energy by 500%, reduce inflammation-causing cytokines by 70%, activate secretions that relieve pain faster, promote healing faster, and decrease scarring over time. Its success ultimately depends on accurate diagnosis; for example shoulder pain could originate in muscles, tendons, bursae discs nerves – FSM is effective against all these sources and can significantly reduce pain for all sources and can significantly decrease pain for all.

FSM can change the structure of your tissue in remarkable ways. Scars will typically soften; trigger points become less painful; and swelling drains. Furthermore, FSM has also been found to reduce nerve irritation and improve nerve signalling – it remains unknown exactly why these changes take place, however likely factors include:

As long as the appropriate frequency is applied to tissues needing healing, results should be almost instantaneous. This is especially true when used for pain management; frequency therapy helps ease it by reducing inflammation, stimulating production of endorphins (the body’s natural painkillers) and increasing nerve conductivity.

FSM frequencies can also help heal scarring, fibrosis and adhesions by stimulating cell regeneration – making FSM an extremely versatile therapy option.

FSM stands out as a unique form of manual therapy by reaching deep within muscle tissues to soften rather than simply relax them – this makes it particularly helpful in relieving musculoskeletal pain, and often results in lasting relief of symptoms.

It’s Easy

Frequency Specific Microcurrent (FSM) is an easy and noninvasive physical therapy treatment, proven effective against numerous conditions including fibromyalgia, chronic fatigue syndrome and myofascial pain syndrome as well as numerous pathological disorders. FSM has also proven useful in relieving nerve and muscle pain from injury as well as treating shingles/herpes simplex virus infection using pairs of frequencies with very low microcurrent amperage currents based on biologic resonance; unlike TENS which blocks pain messages by overwhelming nerves FSM actually increases energy and optimizes cell function compared to TENS which blocks pain messages by overloading nerves

Injuryd tissue often exhibits higher electrical resistance and decreased capacitance, impeding the natural flow of bioelectricity that is essential to optimal functioning. Applying microcurrent to injured areas reduces resistance while also reestablishing cellular capacitance for greater bioelectricity flow – essential components in healing that alleviate pain as well. Research has also demonstrated FSM’s potential to significantly boost ATP levels within cells to restore optimal functioning tissues and organs.

An experienced professional will use a highly precise sequence of frequencies to identify the ideal ones for treating your condition, which are determined through direct observation of how your body responds. Once identified, these appropriate frequencies can then be utilized during sessions that address them effectively.

Most patients see an improvement in their symptoms after just one treatment; however, everyone responds differently and lasting effects may take multiple sessions.

FSM is generally safe; however, pregnant women, those with pacemakers, implanted pumps or uncontrolled seizures as well as people using pacemakers should not undergo this therapy as there may be unwanted side effects associated with it. No known adverse side effects have been linked with FSM treatments.

If you would like to experience this innovative treatment approach for pain management or other health concerns, contact your Synergy practitioner and arrange for a consultation session. They will be more than happy to address any queries about how it can help regain control of your health!

July 18, 2024|Editorial

The Benefits of Metatron Bioresonance Scanning

METATRON is the newest non-linear health diagnostic scanning machine. This innovative machine provides an efficient means of identifying imbalances and energetic disturbances as well as tracking treatment outcomes.

The METATRON NLS scan can quickly and effectively pinpoint factors compromising one’s health, such as emotional strains, toxins, pathogens and energetic disruptions – as well as providing practitioners with insight to tailor tailored treatment approaches for individuals.

Bioresonance

Bioresonance therapy is a natural method of realigning the natural frequencies in your body, using frequency stimulation of active points of the body to address numerous ailments such as pain management, digestion and energy. It is an excellent non-invasive solution without taking medications – the machine simply detects oscillation characteristics in cells and compares them against an ideal blueprint; if out-of-alignments exist then counter frequencies will be released that correct these issues to promote healing of stress, allergies and hormone imbalances in a non-invasive fashion – providing immediate relief from symptoms associated with these conditions!

The METATRON is an innovative bioresonance diagnostic device, using cutting-edge quantum physics research, to detect pathological processes on a molecular level in your body and identify their source – making the METATRON truly special and unique; scientifically validated techniques linking ancestral medicine with quantum physics are only ever achieved with devices like this one!

METATRON records electromagnetic waves produced by each cell, tissue and organ of your body during scanning. These signals are decoded and interpreted into computer models of organs to display where problems lie as well as provide a rough forecast of future health dynamics.

This device can help identify the cause of your problems and suggest remedies, including allergens, food sensitivities, toxins and heavy metals – as well as assess your body’s reaction to certain substances – giving an effective alternative way of alleviating allergies without medication.

BICOM stands out by operating at extremely low frequencies, eliminating any risk of electric shock and making it suitable for people of all ages – even babies and children! Furthermore, its noninvasiveness makes it suitable for use alongside therapies like acupuncture to provide effective treatment of chronic illnesses.

Chakras

Humans possess a complex electromagnetic field which manifests as various colors around the body, known as chakras. This energy system influences one’s emotional and physical wellbeing as chakras connect to various organ systems with specific vibration frequencies; an examination using 17D NLS Metatron can identify imbalances within these organs that might indicate physical or emotional factors as causes.

The NLS Metatron can detect toxins in your body as well as detect allergies to food or medicines, and check for any bacterial infections and parasites which could be the source of many health issues. Furthermore, it can even detect cancer early enough that doctors can treat it before it spreads further and becomes an urgent health problem.

Metatron bioresonance uses quantum physics to scan your entire body, with each organ possessing an electromagnetic vibration which corresponds with body vibration frequency and detected by NLS Metatron as 3-D images on screen. It’s world’s most advanced nonlinear scanner able to identify any imbalance or toxic bacteria or fungi.

At an NLS Metatron session, this device sends frequencies directly into your organs, cells and hormones. Once collected, this data is converted into digital form before decoded into a comprehensive health report including recommended treatments and supplements as well as providing an in-depth view of both physical and emotional wellbeing.

The NLS Metatron was developed by the Institute of Practical Psychophysics as an all-in-one hardware and software nonlinear diagnostic scanner and therapy system. Capable of scanning without harmful effects, and quickly pinpointing contributing factors for disorders in just minutes; its accuracy in finding acute and chronic processes as well as predisposition towards certain diseases exceeds 90%; additionally it has proved successful at treating mental and emotional imbalances effectively.

Quantum physics

Quantum physics represents a revolutionary break with conventional ideas about our world, positing that matter behaves in unexpected ways that have significant ramifications for science and technology in general. Pioneered by such great minds as Niels Bohr, Albert Einstein and Werner Heisenberg.

One of the core concepts of quantum physics is wave-particle duality – or objects having both wavelike and particle characteristics simultaneously. This phenomenon refers to objects being comprised of both waves and particles. Classically speaking, “wave” denotes continuous patterns while particle refers to discrete particles; this idea stems from quantum fields emitting energy in discrete amounts called quanta; light itself can exist both ways at once; the quantum model provides more accurate representations while also helping scientists examine matter’s substructure more thoroughly.

The metatron is a non-invasive diagnostic device that applies the principles of quantum physics to your body’s electromagnetic fields and subtle energy interactions, using their vibration measurements against those assigned as norms for healthy organs in your system. It can detect problems early, before they lead to serious health concerns. It works by measuring the vibrations from all organs and organisms within your system against norms that have been determined as healthy by measuring vibrations across every part of it and comparing this data against healthy norms that have been established for each organ/organ system/system with those assigned healthy norms established as norms against norms assigned healthy organs or systems within that can detect issues at an early stage if any arise.

Data collected by this software is then analyzed, giving a report of your overall health status. Additionally, it can detect toxic bacteria, fungi and viruses in your body for detection purposes and creating a personalized treatment plan tailored specifically to you and your conditions.

The METATRON NLS (Non-Linear System) Scan is a cutting-edge diagnostic technology utilizing quantum physics principles to provide in-depth analyses of your body’s electromagnetic fields and subtle energy interactions. This device can identify disease by measuring an organ’s energetic deviation from its ideal norm – this information is then displayed on your computer screen in three-dimensional graphics form – it also detects abnormalities within the musculoskeletal system as well as microorganisms resistant to modern antimicrobial treatments.

Electromagnetic fields

Human bodies are enveloped by electromagnetic fields that interact with cells and tissues of our organism, helping regulate vital processes while also shielding us from pathogens. Bioresonance scanning can detect imbalances in this electromagnetic field of the body to reveal their causes; it is a non-invasive and painless procedure which can be performed either at home or by visiting a doctor’s office.

The METATRON NLS scan analyzes your body’s electromagnetic field to detect disturbances or imbalances in its harmonic synchronization, and identify areas of disharmony within your body allowing for changes that enhance health and well-being. Based on the principle that each organ or tissue emits its own vibrational frequency, deviations in these frequencies can be detected and corrective frequencies administered to restore balance and harmony if required. It can also identify any underlying causes and suggest the most suitable remedy to remedy them; using NLS scanning technology you can identify these issues before taking steps that improve health or well-being.

Instead of waiting until disease has already emerged to detect it, the Metatron NLS scanner allows early identification of imbalances – so you can take preventative steps before it becomes manifest. Furthermore, this device provides insight into future dynamics for diseases three or five years in advance of initial complaints appearing.

NLS diagnostics software facilitates a three-dimensional scan of the entire body, including cells and mitochondria. It reveals any bacteria or parasites present, as well as pinpointing where pathology occurs in relation to one another. Furthermore, this system can identify ongoing pathological changes as well as detect ongoing pathological processes as well as identify any DNA abnormalities as well as choose an effective therapy plan that promotes self-healing while preventing future disease recurrences.

Metatron Bioresonance is a world-leading medical device comprised of both software and hardware (torsion generator). It has been certified as a torsion wave nonlinear diagnostics and therapeutic device and currently used at Bay Osteopathy and Wholistic Health at 71 Centennial Circuit, Byron Bay Industrial Estate NSW Australia.

July 18, 2024|Editorial

Can Doxycycline Reverse Aging?

Doxycycline is an antibiotic with anti-ageing properties. Research shows it can reverse signs of aging in mice by reprograming their epigenetic status.

Excess alcohol consumption is associated with cardiovascular diseases and an acceleration in cell aging. Scientists have demonstrated that doxycycline reduces ethanol-induced cell aging in endothelial cells.

1. Anti-aging

Doxycycline not only offers anti-inflammatory benefits, but it can also reverse aging by stimulating mitochondrial biogenesis and inhibiting the expression of mTOR to lower ROS levels and cell senescence. Doxycycline has been used to treat cardiovascular diseases and cancer; however, its benefits have yet to be proven; most commonly used for COPD symptoms reduction but can be used against osteoarthritis and acne as well.

Researchers from the University of Pennsylvania led by Profs Takahashi and Yamanaka conducted a groundbreaking study using doxycycline to partially reprogram adult cells back into pluripotent stem cells using Takahashi and Yamanaka’s model from 2006. Following that step, these new stem cells were differentiated into heart cells in order to test whether or not they could help protect vascular aging; and results demonstrated that mice treated with doxycycline had lower blood pressure, longer lifespans and fewer teratomas as well as epigenetic markers of aging.

Ethanol has long been recognized as a risk factor in cardiovascular diseases and linked to accelerated aging of human umbilical vein endothelial cells (HUVECs). A drug screening panel of 170 drugs was evaluated and it was discovered that doxycycline inhibited toxic molecular events caused by excess alcohol exposure – up to 400 mM with or without doxycycline; 10uM alone did not cause cytotoxicity in HUVECs.

Ethanol accelerates HUVEC telomere shortening, leading to cell senescence and eventually cell death. Ethanol-treated cells also had reduced lamin b1 expression. Doxycycline reversed this ethanol-induced senescence by increasing lamin b1 protein expression as well as inhibiting activation of mTOR and p-S6 activity – this helps decrease oxidative stress, delay cellular senescence, extend lifespan as well as stimulate autophagy activity while increasing autophagy function p-mTOR also stimulates autophagy while increasing autophagy function as well. Furthermore, Doxycycline increased GADD45 expression which plays an essential role in controlling cells’ stress response mechanisms.

2. Skin rejuvenation

Doxycycline can help reverse aging by improving your skin health. It does this by decreasing bacteria on your skin, which in turn prevents acne breakouts. Furthermore, its anti-inflammatory properties may help alleviate redness associated with rosacea and it has anti-wrinkle and fine line properties as well. Finally, its anti-ageing benefits may help diminish signs of aging such as wrinkles and fine lines by blocking enzymes that break down collagen.

Enhancing skin elasticity also can help make you appear firmer and younger as it helps increase collagen and elastin synthesis – the proteins responsible for keeping your skin tight and smooth.

Doxycycline can reverse aging by improving your blood flow. It does this by reducing inflammation and encouraging new blood vessel formation; additionally, doxycycline may prevent blood clots from forming in your arteries – something which often contributes to heart disease.

Excess alcohol consumption is a risk factor for cardiovascular diseases and accelerates cell aging in human umbilical vein endothelial cells (HUVECs). To evaluate whether doxycycline could inhibit this ethanol-induced senescence process in HUVEC, we performed a scratch assay on 6-well plates containing HUVEC cultured with 400 mM ethanol or an combination of 400 mM ethanol and 10 ug/mL of doxycycline for four days before harvesting cells to measure their telomere length–an indicator of cellular senescence.

3. Anti-cancer

Doxycycline, a semi-synthetic second generation tetracycline antibiotic, is a broad spectrum antibiotic with antimicrobial and anti-aging effects. It targets the 30S subunit of the ribosome to inhibit protein synthesis by bacteria; and has anti-inflammatory and anti-aging benefits as well as acting as a senolytic drug which selectively kills and removes senescent cells that accumulate with age; this process is associated with several diseases as well as premature aging; inhibiting p-mTOR and its downstream signaling molecule p-S6 reduces cellular senescence while simultaneously increasing autophagy processes.

Doxycycline’s senolytic effects may be enhanced when combined with other drugs, particularly methotrexate (another senolytic medication). Researchers believe this combination may improve health-span and longevity by decreasing cancer and other inflammatory diseases, while its anti-senescence benefits are enhanced further by inhibiting p-mTOR and its downstream signaling molecules such as p-S6 and p-mTORC1. Blocking this pathway decreases cellular senescence caused by short telomeres while increasing autophagy to clear away damaged proteins/organelles from damaged organelles/proteins/proteins/molecules from damaged proteins/organelles/ cells from damaged proteins/organelles that accumulate over time, potentially improving overall health by slowing its effect; inhibiting these molecules also provides further boost to help slowing its effects by slowing their effects through increasing autophagy which cleans damaged proteins/organelles from cells while simultaneously clearing damaged proteins/organelles from autophagy to clear damaged proteins/organelles/.

BioRxiv* published a study showing that doxycycline partially reverses aging in progeroid mice. Researchers administered this medication via retroviral vector containing OSK cassette and extended their lifespan by 109%.

Mitochondria, the organelles responsible for producing 90 percent of the chemical energy cells require to survive, have been found to become less functional with age and linked with cardiovascular disease, diabetes and Alzheimer’s dementia. Horvath and Raj used epigenetic methylation clocks to assess whether doxycycline could reset mitochondrial DNA methylation levels.

Ethanol can accelerate human umbilical vein endothelial cells’ (HUVECs) aging by shortening telomere length and cell senescence, so researchers screened 170 compounds to find one which would counter ethanol’s adverse molecular events; they discovered doxycycline significantly restored ethanol-accelerated telomere length and migration of endothelial cells as well as increasing MMP-9 and TIMP-2 expression levels while simultaneously decreasing proinflammatory cytokines TNF-alfa and IL-6 proinflammatory proc inflammatory proc inflammatory pro inflammatory pro inflammatory cytokines TNF-alfa and IL-6

4. Hair growth

Tetracyclines have also been found to stimulate hair growth, increasing levels of certain proteins while inhibiting another one known as cyclooxygenase-2 (COX-2). Furthermore, these antibiotics have also been demonstrated to decrease production of certain proinflammatory molecules that promote aging such as cytokines and prostaglandins; their action being thought due to antagonism with their target enzymes.

Researchers conducted several experiments where they infected mice with a genetic mutation that depletes mitochondrial DNA (mtDNA depletion). After four weeks, otherwise healthy animals showed physical changes reminiscent of natural aging: graying and thinning hair; skin wrinkles; slow movements and lethargy; dysfunctional hair follicles and abnormal sebaceous glands. Notably, however, when this mutation was turned off these phenotypes could reversed back.

These observations have been confirmed through longitudinal analysis of data from a large, placebo-controlled trial of doxycycline and its derivatives. The primary analysis involved linear regression to estimate change in normal scores between baseline and 2 years; independent variables included baseline normal score, gender, sex and dichotomous treatment (0 for placebo/1 for doxycycline); as planned in advance there was also an evaluation for whether separate analyses of men and women would be necessary.

Results revealed that doxycycline significantly delayed the onset of aging symptoms for both males and females, even though they all received identical doses of the medicine. Differences in symptoms between groups were linked with mitochondrial oxidative stress influences on COX-2 production within cells; those receiving doxycycline experienced higher COX-2 production than placebo groups whereas their levels of other inflammatory molecules remained similar across both.

To maximize the anti-aging benefits of Doxycycline, it is vital that it is taken with food. This ensures that it won’t lodge in your esophagus and cause discomfort or irritation.

July 18, 2024|Editorial

Magnetic Resonance Therapy for Post-Traumatic Stress Disorder (PTSD)

At Newport Brain Research Laboratory and Brain Treatment Center, magnetic resonance therapy (MRT) is employed as an effective method to treat posttraumatic stress disorder (PTSD). MRT works by manipulating activity patterns in brain networks associated with this condition using magnets.

Two RCTs have investigated second-generation TMS modalities for treating PTSD. The first randomized 103 veterans to active or sham 1Hz TMS to the DLPFC prior to weekly CPT sessions.

Symptoms

Post-Traumatic Stress Disorder, or PTSD, is caused by any kind of trauma – war, sexual assault, car accidents or severe illness can all lead to it – as well as any subsequent events like abuse, loss and death of loved ones. People affected may experience intense and persistent feelings of fear, anxiety or depression which worsen over time and make functioning normally increasingly challenging; symptoms can linger for months or years and include nightmares, flashbacks and difficulty sleeping; lack of concentration as well as emotional numbness are just some symptoms associated with PTSD.

MeRT (Magnetic E-resonance Therapy) is a noninvasive treatment method using brainwave analysis to realign neural pathways in your brain. The process includes placing coils around your head and applying magnetic pulses that affect how neurons communicate between each other, with your doctor then being able to adjust intensity levels of magnetic fields in order to target areas that need realigning in your mind. MeRT may be beneficial in improving mental health as it offers alternative solutions compared to medications or other forms of treatment.

A former Marine helicopter crew chief reclines in a medical suite with eyes closed while an ex-Army squad leader holds a paddle-shaped wand against his forehead, providing short bursts of electromagnetic stimulation to his frontal lobe of brain. For six seconds, this device produces a staccato rhythm as short bursts are delivered directly into his brain’s frontal lobes via electromagnetic stimulation.

This phase II trial used double-blind, placebo-controlled stimulation of both right and left DLPFC with active 20Hz rTMS to reduce symptoms associated with DSM-IV diagnosed PTSD in 30 patients diagnosed using DSM IV criteria. Each condition resulted in significant reductions of core symptoms including hyperarousal, vigilance, intrusive thoughts and emotional numbness – though right condition had larger effect than left condition.

Cortical MeRT should generally be administered only if pregnant or breastfeeding patients can avoid certain absolute contraindications that require close protocol attention, but can typically be avoided by those not pregnant or breastfeeding. These include a history of seizures, pacemakers or defibrillators, pacemakers/defibrillators, pacemakers or defibrillators, pacemakers or defibrillators, pacemakers or defibrillators, pacemakers or defibrillators, pacemakers or defibrillators implants aneurysm clips aneurysm clips ear implants cochlear implant and metallic foreign bodies present within the brain (excluding titanium). In addition to absolute contraindications discussed with your physician; relative contraindications include mental illnesses including bipolar Disorder Types I/III disorders Types; Tinnitus; depression.

Diagnosis

As soon as PTSD first surfaced in the 1990s, doctors believed it to be caused by an abnormal brain circuit that shifted memory and emotional processing toward the right side of the cortex. Treatment options typically included psychotherapy sessions aimed at forcing patients to revisit traumatic events as well as antidepressant medications belonging to the SSRI class.

However, these treatments can often have unpleasant and even dangerous side effects. Another possibility is eye movement desensitization and reprocessing (EMDR), which uses rapid eye movements to help victims process trauma memories – however this process is time consuming, costly, and has a high dropout rate.

BrainsWay’s noninvasive MeRT therapy uses magnetic stimulation of brain structures and networks associated with posttraumatic stress disorder (PTSD). Our device analyzes your brainwaves to ensure optimum treatment results – offering a safe yet effective approach to mental wellbeing improvement.

Jon Warren, a former Marine helicopter crew chief, relaxes comfortably at the Brain Treatment Center – a nonprofit offering free sessions to veterans – in a medical suite. Warren has experienced remarkable transformation since spending most of his life wracked with guilt over failing to rescue fellow soldier from burning Humvee that crushed them during Iraq deployment 2006.

No longer plagued by nightmares or flashbacks, he no longer harbors suicidal thoughts and can spend long days with his wife. Additionally, his 10-year-old son with autism no longer requires one-on-one aide at school and is reading at a high school level, passing spelling tests effortlessly.

Even with impressive clinical trial results, researchers are still exploring optimal TMS settings for treating PTSD. Studies have examined frequency, pulse duration and intensity as well as delivery modes including sTMS and TBS; yet only few have explored long-term outcomes of PTSD symptom improvement.

Treatment

Neuroimaging and electroencephalogram (EEG) studies indicate that altered cortical excitability contributes to the pathogenesis of posttraumatic stress disorder (PTSD). Particularly, the ventromedial prefrontal cortex (vmPFC) and amygdala are implicated. Furthermore, several animal and human clinical studies demonstrate how noninvasive brain stimulation such as rTMS or tDCS to these regions may alleviate PTSD symptoms (12-17). One rTMS treatment to the vmPFC reduced symptoms while another using tDCS in amygdala improved symptoms as well as normalized EEG activity (18-20).

As well as psychotherapies such as CPT and PE, TMS combined with these treatments has been explored through some RCTs (21). One such RCT employed a modified version of the imaginal exposure protocol which involved self-guided exploration of trauma-related imagery while speaking aloud while receiving weekly TMS sessions; its results were similar to that of using just the imaginal exposure protocol alone, yet greater than using PE alone.

More recent research has made use of resting-state fMRI to measure predictors of clinical response to TMS (23-28). Results from two studies suggested that participants who responded well had increased within-network connectivity within the DMN as measured by resting-state fMRI; by contrast, those who didn’t respond had reduced within-network connectivity and displayed poorer PTSD symptom reduction on the CAPS scale.

sTMS, the second-generation TMS modality, uses three rotating magnets to deliver relatively low energy triplet bursts of pulses at more precise frequency levels (synchronized to each participant’s intrinsic alpha frequency). A pilot RCT randomized veterans with both PTSD and MDD to either active sTMS treatment or placebo for one month follow-up; active sTMS was found to significantly reduce both symptoms simultaneously.

Jin has been using off-label sTMS treatments to treat veterans for PTSD since 2013. According to his estimates, about 100 veterans have undergone treatments; most had given up with traditional approaches offered through VA such as behavioral therapy and medications. Many reported their PTSD symptoms have significantly reduced or been entirely eliminated and this improvement has continued at least since 2013. Going forward, researchers hope to assess sTMS’ potential in treating other disorders such as depression anxiety addiction and tinnitus.

Results

TMS uses an electromagnet to deliver pulses of magnetic energy that stimulate brain cells and increase their activity, approved by the U.S. Food and Drug Administration for treating depression but researchers have also discovered it can alleviate PTSD symptoms in veterans. TMS differs from other treatments by not requiring surgery or medications – the results from studies indicate it’s effective as either monotherapy or in combination with psychotherapies.

Studies have demonstrated the efficacy of TMS for relieving combat-related PTSD symptoms, such as depressive and anxiety symptoms. One such study involved coexisting PTSD and MDD patients receiving 10 sessions of either 1 Hz or 5 Hz TMS to the left DLPFC; those receiving TMS showed greater improvements in both depression (though not anxiety) symptoms than a control group; another recent retrospective case series study demonstrated 1Hz bilateral DLPFC TMS improved these same areas, though its effect size was smaller.

Another small pilot RCT randomly assigned nine participants to either active versus sham rTMS of their right DLPFC during an imaginal exposure protocol. Participants experienced significant decreases in PTSD symptoms on CAPS assessments that were sustained through follow-up.

These studies provide encouraging findings, yet further investigation is required to identify optimal stimulation parameters and laterality, and identify predictive biomarkers of response. FMRI and EEG measurements may help detect patterns of network connectivity that correlate with clinical responses; an increase in salience network (SN) connectivity has been linked with posttraumatic stress disorder (PTSD).

Future research may examine the effects of different rTMS protocols on different symptoms clusters associated with PTSD and determine which targets are more or less effective than others. Furthermore, conducting a large-scale controlled trial would allow researchers to ascertain its safety and efficacy among PTSD veterans from multiple populations. One group of scientists is raising funds for such an endeavor with plans to use two MRT devices that cost around $50,000 each in double-blind clinical trials of TMS devices for treating PTSD veterans.

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