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Information Wellness Blog

Detailed Reviews and Guides about energy and informational health and wellness

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September 22, 2024|Editorial

Ultrasonic Resonant Frequency Therapy Device Patent

The device combines multiple wave energies and can be used to destroy malignant cells more effectively than existing audio frequency devices.

The invention relates to a system and method for providing ultrasound therapy at multiple user-selectable frequencies using one applicator sound head, as well as methods for identifying therapeutic resonant frequencies.

Methods of determining resonant frequencies

electromagnetic waves have long been used to control atomic and molecular particles, including bacteria cells and diseased tissue. For maximum effectiveness, therapeutic resonant frequencies must match those naturally resonating with materials; to do this accurately, methods have been devised that allow precise determination of therapeutic frequencies that better reflect natural resonance frequencies of materials – including providing more precise results than trial-and-error techniques and also allow the identification of specific genomic materials, atoms or molecules requiring therapy.

Researchers used magnetic resonance imaging (MRI) on mouse tumor-bearing mice with cancerous tumors and measured their resonant frequencies using magnetic resonance imaging systems, before treating with drugs that activate protein phosphatase 2A (PP2A) enzyme activators drug to decrease tumor resonant frequencies; suggesting their importance in cancerous tumor development.

Methods used for determining resonant frequencies take into account the refractive index of the medium in which genomic material, atoms or molecules are being utilized. This allows for more precise and accurate correlations between their findings and natural or therapeutic resonance frequencies of materials being studied.

Researchers used magnetic resonance imaging machines to conduct studies on mice carrying flank tumors of human neuroblastoma cells from SK-N-AS strain, and measured the resonant frequencies using computer software. Tumor resonant frequencies differed significantly from those in normal tissues due to higher concentrations of phosphorus present within tumors, leading to more vibrational modes being activated than usual tissues.

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These techniques of detecting resonant frequencies also have applications outside the laboratory, such as producing compressional pulses within living organisms. They involve shaping an overmodulated audio wave in a radio transmitter and sending its vibrational frequencies through a gas-filled tube; when they encounter target tissues they will resonate and cause them to vibrate causing them to reflect back to the source where they can then be detected and utilized for various biophysiologic effects.

Devices for determining resonant frequencies

This invention concerns devices for identifying therapeutic resonant frequencies through sound wave energy. These devices utilize modulated audio frequencies to produce electromagnetic waves with wavelengths in the ultrasonic range that exert compressional forces inside cells and organisms, inhibiting microbial growth while treating diseases or conditions. Furthermore, the devices also generate subharmonic frequencies multiples of fundamental frequencies; such frequencies can be more effective at modulating genetic activity than fundamental frequencies alone.

Determining resonant frequencies with this method is much simpler and faster than using trial-and-error. Furthermore, it takes into account an appropriate electromagnetic refractive index of a medium and allows for faster identification of therapeutic resonance frequencies.

This patented technology can be used to effectively prevent or destroy microorganisms such as viruses, bacteria and parasites. It works by shaping an overmodulated radio wave pulse from a transmitter and sending it down a gas-filled tube, where its overmodulated form creates a wave form capable of penetrating into tissues within the body to produce physiological effects.

To identify the resonant frequency of genomic material, the length of DNA or RNA biomolecular chains is measured; this provides a wavelength measurement specific to that piece of genomic material. Furthermore, nucleotide base pairs in DNA double helixs can also be measured and utilized to ascertain frequency measurements.

Once a resonant frequency has been identified, the next step should be comparing it with other frequencies in order to find its resonance point – where an amplitude difference exists between two frequencies and then finding their respective resonant frequency characteristics of interest by comparison. Once found, this step allows devices such as ultrasound to locate it easily. Once found, devices then determine its resonance frequency characteristics relative to other frequencies for target material evaluation purposes and compares their amplitude frequency characteristics against each other in order to locate resonance points and establish resonance points by comparison between themselves compared with them and then finding its resonant frequency characteristics by comparison between its amplitude frequency characteristics with others frequencies compared with each frequency that has its amplitude frequency characteristic when compared with others. Once established this step allows devices to locate resonance points where amplitude differences exist between one frequency is larger than another when amplitude differences occur in terms of comparison of material related to target material comparison; device will then determine its resonant frequency by comparing its amplitude frequency characteristic with others and determine its resonant frequency characteristics with others frequencies to find its resonant frequency characteristic of any target material comparison to other frequencies used in measurements taken of target material characteristics versus others found.

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This patented technology combines diverse wave energies to generate composite energy waves capable of breaking down and killing microorganisms without harming healthy tissue, providing a safer way of treating illnesses and diseases. Furthermore, this method may even be used to inhibit cell malignancy by disrupting cancerous cell mitosis without harming healthy cells or tissues during mitosis.

Devices for generating resonant frequencies

Resonant frequencies generators use electromagnetic energy to interact with genomic materials such as DNA and RNA, producing bio-physiologic effects on cells and microorganisms that either inhibit, debilitate or stimulate them depending on the frequency used. Their effectiveness depends on both ease of identification as well as efficiency when used with suitable devices and delivery systems.

Existing devices can identify resonant frequencies for specific genome materials, but may not always have access to those frequencies for use with their frequency-emitting devices. This is usually due to needing long coaxial cables between components such as radio transmitter and amplifier/tuner; such cables degrade pulse envelope quality and decrease modulation frequency pass band pass rates significantly. An improved device would eliminate such long lengths of coaxial cable completely while greatly improving operational attributes by many orders of magnitude.

Improvements to this device involve installing a new transmitter and accessory components that enable it to output higher frequency ranges without degrading its pulse envelope. With these upgrades in place, this improved device is capable of producing compressional waves extending into ultrasonic range, which can then be directed toward tumors or viral infections in various parts of the body; their vibrations create beat frequencies within cells or organisms that resonate with their DNA or RNA structures and resonate back.

The device also allows users to identify resonant frequencies for smaller portions of DNA or constituent components within a genome, so they can more precisely target their treatment of DNA/RNA that needs treating. Furthermore, users can program this device to select optimal frequencies for any given patient while monitoring how effective treatment has been.

The new transmitter and its attached components boast much faster rise and fall times than their existing device, enabling shorter pulses with higher modulation frequencies to be produced more quickly than before. This upgrade significantly boosts modulation capability, commercial viability and the creation of physiological effects by many times over.

Methods of generating resonant frequencies

Many therapeutic devices emit not only their basic frequency – known as the fundamental frequency – but also multiple harmonic frequencies, known as harmonic multiples of fundamental frequency, that provide more effective methods of modulating genetic activity. Resonant frequencies are created by dividing fundamental frequency by positive integer to determine harmonics and subharmonics; then these frequencies can be programmed into frequency emitting devices to be released when targeting genomic material.

Resonant frequency of an object correlates with its length and can be detected within its environment. DNA/RNA chains possess natural resonant frequencies correlated to their length which interact with electromagnetic waves in which they are immersed, emitting energy waves that are detectable by human bodies and can even prevent diseases and conditions that affect humans or animals as well as agriculture, water systems, food processing facilities etc. This technology can be applied in many applications for prevention or treatment of microbiological and biochemical events including human and animal illnesses as well as agriculture systems water systems food processing systems etc.

This invention describes a method for determining resonant frequencies for molecules and cells using the fact that their structures emit frequencies with differing wavelengths depending on their structures. In particular, WatsonCrick model of base pair spacing offers a convenient method of translating DNA linear length into its frequency in electromagnetic spectrum; using this information to identify resonant frequencies useful in diagnosing therapeutic effects on these molecules.

Method of the present invention may also be utilized to generate lower audio range resonant frequencies. To do this, an initial therapeutic resonant frequency can be divided by 2, or some power of two as necessary until reaching audio-range resonant frequencies that resonate. These related frequencies are known as octaves in music and will resonate as such when placed next to each other.

This patent describes an improved frequency therapy device which allows for higher frequency transmissions with reduced degradation to pulse envelope. This is achieved using a new transmitter with its associated components – amplifier, tuner, plasma tube antenna type. Furthermore, this device boasts rise and fall times of up to 40 nanoseconds compared to existing devices – a substantial advancement.

September 22, 2024|Editorial

Reiki Distance Healing

Reiki distance healing is an incredibly effective way of sending energy outward, directly benefiting both its recipient and practitioner.

Practitioners begin their Reiki experience by creating a peaceful space free of distractions, and entering a meditative state to connect with universal energy. Reiki symbols may also be used to direct this energy towards specific goals.

Benefits

Reiki is a noninvasive, natural energy healing technique. It promotes relaxation and balance while acting as a complement therapy for various health conditions, from relieving pain to improving sleep to increasing immunity. You can receive treatments in-person or remotely; just make sure that before embarking on any new reiki treatments it has been cleared with your physician first.

Distance healing is an incredible form of Reiki, enabling you to connect with another’s higher self across time and space – whether human, animal, or both! – by sending love and light from anywhere in the world – whether that means sending it for physical healing purposes such as those sick with illness, dying pets, emotional healing needs, goals/intentions fulfilled, past and future reiki healing energy or simply wanting peace for oneself or a goal reached!

While many remain skeptic of energy healing, distant Reiki sessions can still provide effective results. Both practitioner and recipient need to set up a time for the session; those receiving Reiki should make themselves as comfortable as possible in an undisturbed area with no noisy distractions, including turning off phones or placing them on silent. They should also prepare themselves for possible detoxification processes which may include physical as well as emotional changes.

After each session, participants should take time to reflect upon and process their experience by reflecting, journaling or mediating – this will enable them to fully embrace all the benefits gained from it. It is also recommended that they hydrate regularly with water while listening to what their body needs – this may include exercise, sleep or meditation.

Distance healing sessions can also be more affordable because the practitioner does not need to pay rent. This makes distance healing ideal for busy schedules as well as people living far away or those with health or mobility concerns who cannot easily travel in person to a practitioner’s office.

Techniques

Reiki energy can be sent from a distance through various techniques. Reiki practitioners may utilize remote healing symbols or telepathic connections to connect with their recipients’ energy fields; either way, energy transferred during distance healing sessions remains just as potent.

At a Reiki distant healing session, recipients may experience feelings of peace and relaxation as light washes over them. Some may also feel tingling sensations or temperature changes within their bodies – some even fall asleep! What matters most in reiki sessions is intention – with positive intentions set out from both practitioner and recipient, the chances are slim that there will be any negative side effects due to receiving Reiki healing sessions.

Some practitioners provide remote aura reading services. An aura reading requires gathering photos and dates of birth as well as using the Usui power symbol to energize hands and chakras for around 10 minutes before calling upon their Reiki distant healing symbol three times to send Reiki out into the universe while visualizing their friend’s face and visualizing sending it Reiki energy. While scanning, practitioners will need to pay particular attention to all chakras and levels of being.

An alternative way of sending Reiki remotely is to focus it on specific goals. A practitioner would write their goal on an index card and draw the distant healing symbol over it before holding up the card in their hand and repeating “HSZSN be with me” and “reiki is love and light.”

Before conducting distance Reiki healing sessions, reiki practitioners must obtain permission from both parties involved. Otherwise, recipients could experience unwanted side effects from these sessions such as taking on their practitioner’s karma or feeling an energetic cord connecting them both; cutting it at the end of each session is important in this respect.

Convenience

Distance healing allows energy practitioners to provide sessions to clients who do not have an energetic healer nearby, providing more people access to this holistic therapy and reaping its many advantages. Reiki’s limitless reach proves just how far its healing power stretches – the effects can reach far and wide!

To conduct a Reiki distant healing session successfully, an energy practitioner must first be attuned with the reiki frequency and symbols before choosing their location for healing sessions. They should use music, candles or ambient lights as distraction-free zones that help create sacred spaces where people can get into their proper mindset for receiving treatments remotely. It’s advisable that patients are aware they will receive treatments at distance in advance so they can mentally and physically prepare.

Once a practitioner has empowered their hands and activated their reiki symbol, they should focus on visualizing who it’s directed toward and their energy will reach. Writing down their name on paper might also help – or holding it while sending energy directly towards that individual is another powerful method. For an extra effective healing session, using one or more symbols from level two reiki training might be best.

Reiki is a spiritual healing modality used to address physical, mental and emotional health. It makes an excellent complement to traditional medical treatments as it does not interfere with any medicine or therapy being taken by its user. Reiki has quickly become one of the world’s leading alternative healing techniques and continues to gain worldwide popularity.

An energy healing session of Reiki distant healing may induce feelings of warmth and tingling for its recipient, bringing comfort from physical symptoms as well as relief from tension and pain relief, inner peace, and expanded consciousness. Reiki addresses underlying issues which cause physical or mental discomfort by working directly on an energetic level.

Safety

Reiki is a holistic healing energy therapy designed to foster physical, emotional and spiritual well-being. Though there is limited scientific research backing its efficacy, most experts agree it can safely be added into one’s self-care routine as an additional supplement to traditional medical treatments. Before giving Reiki energy therapy a try though, it is essential that all necessary safety measures be observed.

First and foremost, make sure your practitioner is reputable and experienced, adhering to ethical guidelines and maintaining client confidentiality. Also think about whether communication between both of you flows easily; is the relationship comfortable enough that both of you feel understood?

Some practitioners limit their Reiki distance healing sessions to those they’ve personally met and established an ongoing relationship with, while others provide it to anyone who requests it. Furthermore, some may only use it on those they know well who have given permission for them to visit their homes or offices with this symbolism.

For instance, to send Reiki energy to an individual you can refer to either their picture, write their name on paper, or think about them while activating the distance healing symbol and send out healing energy from afar. You could do the same with pets, places or events!

Although yoga cannot replace medical treatment, it can offer relief for pain, stress and anxiety. Furthermore, it can speed recovery after surgery while decreasing side effects associated with chemotherapy or other drugs; and can even ease chronic conditions like diabetes or asthma.

Reiki can also be employed to increase immunity and prevent illness. This method is often utilized by nurses, physicians and other health care professionals who work in high-stress environments with limited opportunities for relaxation.

Reiki can be safely practiced by most individuals, including pregnant women and children. Additionally, Reiki may even be beneficial when combined with complementary therapies like massage therapy – just make sure you consult with a healthcare provider beforehand! For any serious conditions such as chronic fatigue syndrome (CFS), Reiki therapy may help provide relief; but always seek medical advice first before turning to Reiki therapy as treatment option.

September 21, 2024|Editorial

Biohacking Health – A Personalized Approach to Self-Experimentation

Biohacking health is a method of self-experimentation designed to empower individuals and empower themselves with knowledge about their bodies in order to optimize performance and longevity. Common biohacks include sauna and cold exposure therapy, nootropic supplements, red light therapy, wearable devices that track metrics such as sleep and heart rate.

Exercise

Physical biohacking requires optimizing muscle growth and endurance to realize maximum results from workout routines, so many biohackers use a combination of vitamins, tools and diet changes to optimize their workouts and produce maximum gains from their regimens.

Some of these techniques include ice baths, electrical muscle stimulation (EMS), vibration therapy and blood flow restriction training. Others involve nutritional supplementation such as matching one’s genetic makeup with optimal nutritional needs or nootropics that enhance cognition and memory.

Mind optimization is another essential element of biohacking health, including techniques such as meditation and deep-breathing exercises to lower stress levels and enhance mental clarity. Scientific evidence confirms these practices to increase resilience while decreasing cortisol production – all critical factors when dealing with stress hormones like cortisol.

Nutritionally, cognitive biohacking requires eating a nutrient-dense, whole food diet rich in vegetables, fruits, nuts, legumes and healthy fats as well as lean proteins and whole grains. A biohacker’s diet may also include nootropics and senolytics to boost brain power further.

Sleep optimization is another essential aspect of biohacking, and various gadgets and apps exist that can aid in this effort. A light and sound machine used to stimulate the brain during sleep is often utilized by biohackers as an invaluable resource.

Biohacking has quickly become popular among fitness enthusiasts and other people looking to take control of their health, but it’s essential that biohackers remember these techniques are no replacement for leading a balanced lifestyle and receiving regular medical screenings – for instance, full body MRI scans can detect early stage cancers and abnormalities before they become major issues. To stay safe and healthy when trying out biohacking techniques it’s wise to work closely with a physician or wellness expert as this ensures any short-term optimization goals won’t compromise long term wellness goals.

Nutrition

Nutrition is an integral component of biohacking health lifestyle, providing the energy necessary to meet fitness and other wellness goals, while supporting mental clarity and cognitive function. Because of this, many individuals strive to optimize their diets through various dietary practices and supplements.

Common practices among biohackers include eating nutrient-dense foods such as whole grains, fruits, and vegetables; limiting sugar; avoiding processed and refined carbohydrates; and eating plenty of fats to boost metabolic energy. Biohackers may also incorporate intermittent fasting into their diets in order to increase metabolism and aid weight loss; some biohackers even opt for ketogenic diets which restrict carbohydrates while encouraging the body to burn fat as fuel instead.

Biohacking‘s personalized approach to nutrition allows individuals to take full advantage of their individual physiologie. Genetic testing such as nutrigenomics can reveal insight into a person’s specific dietary needs such as food sensitivities or deficiencies that could inform a personalized nutrition plan.

Biohackers know the importance of keeping themselves properly hydrated is also paramount for success in biohacking. Drinking enough water each day can help reduce fatigue, improve skin tone and ensure digestion runs smoothly – it is advised that individuals aim for approximately ten glasses daily as a daily minimum target.

Dietary modifications frequently used by biohackers include taking certain vitamins and minerals, such as vitamin C, omega-3 fatty acids and antioxidants; many also incorporate probiotics into their daily diet for gut health purposes. It is also vital that biohackers get enough sleep – having a regular bedtime routine and decreasing screen time before sleeping will ensure optimal restful and relaxing restful slumber.

Biohacking has grown increasingly popular among those seeking to enhance their health and performance through experimentation and technology. Making small modifications, known as hacks, can have significant effects on one’s wellbeing when combined with exercise and proper diet. While biohacking may seem beneficial to some individuals, critics often see its practice as body shaming or social distancing practices.

Sleep

Sleep optimization is an indispensable biohack to improve health and wellbeing, including by creating a regular sleeping schedule, creating an ideal sleeping environment and avoiding stimulants like caffeine. Sleep-promoting foods may also be included as supplements like Melatonin Glycine Rhodiola Rosea. Achieve adequate amounts of restful sleep has proven its worth in improving metabolic processes, hormone production and stress management in many ways.

Biohackers have adopted several techniques to optimise sleep. One is sleeping in a darkened room, which helps block out light that might disturb our natural rhythms, as well as breathing work – such as slow, deep breathing or the Buteyko method – which consciously controls breathing to improve performance and has many techniques such as slow, deep breathing or the Buteyko method to choose from. All these practices have profound impacts on both mind and body, including increasing cognitive functions, decreasing inflammation levels, improving mood state and strengthening immune systems.

High-powered CEOs and founders have long used biohacks, or “biohacking“, to boost productivity and avoid burnout. Many of these methods, from enzyme injections to $300 sleep rings, lack scientific backing. Water filtration startup CEO Winston Ibrahim swears by NAD+ “brain reboot” injections purported to promote focus and energy levels; other overworked entrepreneurs take microdosing LSD for creativity purposes.

Biohackers seeking mental clarity have turned to neuroplasticity and mindfulness techniques in search of mental clarity. These practices aim to enhance day-to-day cognitive function while protecting against age-related cognitive decline; often combined with nootropic supplements like Rhodiola rosea, Panax Ginseng and Ginkgo biloba for maximum effectiveness.

Biohackers are always searching for new ways to boost their health, while remaining committed to their wellness routines including sleep, diet and exercise. Before engaging in any biohacking techniques or changing any habits in your lifestyle it is wise to consult your physician first as they can offer guidance and advice regarding any new habits which might interfere with existing wellness routines or cause any adverse side effects – this takes time so be patient in your efforts!

Stress Management

Stress has the ability to disrupt physical, mental and emotional health in detrimental ways. Therefore, it’s crucial that individuals actively take steps to combat it by managing it and looking for ways to build resilience if they wish to thrive and reach their highest potential.

Biohacking approaches to mental and emotional well-being focus on identifying imbalances within the body through biomarker testing and functional medicine principles, then crafting a personalized plan to correct those imbalances through targeted dietetic modifications, stress management techniques, sleep optimization strategies or supplementation of various kinds. A biohacking practitioner may monitor progress through regular follow-up appointments and stress testing to ensure the body is responding appropriately.

Biohacking differs from traditional medical treatments in that its main goal is to enhance quality of life, rather than treat disease. Practitioners of biohacking employ various techniques such as breathing exercises, mindfulness, and meditation in order to do just this – such as decreasing physiological stress responses and heart rates while simultaneously improving focus – all vital elements for emotional well-being.

Biohackers rely heavily on cognitive restructuring to strengthen resilience, teaching people how to recognize and challenge negative thought patterns while accepting all emotions without judgment. Furthermore, relaxation techniques like deep breathing or visualization may increase confidence while decreasing anxiety levels.

Emotional biohacking can assist people in building emotional intelligence – an indispensable skill needed for both business and personal success. Caregivers of elderly or infirm loved ones often experience tremendous strain; thus it is essential that caregivers develop effective coping mechanisms in order to maintain both physical and mental wellbeing.

One key tool biohackers employ in their effort to manage stress is hormesis, or controlled stress that is beneficial for the body. Exercise and ice baths can both serve as effective forms of hormesis that stimulate antioxidant production to reduce inflammation and oxidative damage; however too much stress may have the opposite effect and lead to an increase in inflammation response.

September 21, 2024|Editorial

What is a Clark Zapper?

Clark claims that zapping kills parasitic organisms and improves health, according to her book “The Cure for All Diseases”. In it she provides clear instructions for building a shoe box zapper using $20 worth of Radio Shack parts.

Clark asserts that any positively offset frequency can kill bacteria, viruses and parasites when applied with adequate voltage for seven minutes.

How to Use

Clark Zappers are electronic devices designed to combat parasitic infestation, such as flukes and roundworms; viruses; bacteria; mycelium; and fungus using low frequency electricity pulses to kill them off and support healthy tissue. Commonly referred to as bug zappers because they attract bugs, it can also be used against fleas and ticks if desired.

The Zapper was created with safety in mind. Its copper electrodes are equipped with dampening devices that prevent shorting and are connected to its circuitry using a 9-volt battery for use. When activated, it emits positive offset square wave frequencies which resonate with pathogens and destroy them, unlike Royal Raymond Rife’s Ray Machines which only stop at zero voltage levels.

Clark developed her zapper to target parasites in the body using specific frequencies while simultaneously stimulating immunity. Her idea was that eliminating parasites would enable the natural healing process of the body, and daily usage may result in visible improvements within a month for some users.

Many who use zappers find relief for symptoms like diarrhea, sore throats and colds. Furthermore, it has been reported to help alleviate headaches as well as reduce migraine attacks in some instances.

Be sure to carefully read through and understand your zapper’s instructions before using it, as this will provide essential safety guidance and any warnings or cautions that should be observed when handling or operating it. Failure to heed all safety rules could result in serious injuries.

To ensure the optimal functioning of a zapper, purchase one that has been thoroughly tested and meets Clark’s books specifications for frequency and pulse duty cycle specifications. The Frequency Generation brand zapper operates at 30kHz without negative spikes on an oscilloscope, according to these books. This model can also be held with hands apart so both hands receive current. For optimal use it should be used three 7-minute sessions with 20-minute breaks between each session.

Safety

Clark developed an electronic circuit using a 9 volt battery which she believes can kill parasites, bacteria, fungi and viruses. Her “zappers” produce frequencies which zap pathogens by resonating with their natural frequencies to devitalize them and eventually eradicate the problem altogether. She used 555 timer integrated circuit technology and two copper handles or electrodes which the user holds in their hands or places on various parts of the body in order to generate low voltage electromagnetic energy and kill infections at their source.

As these parts of the body conduct electricity, using a zapper should not come into direct contact with eyes, inner ears or testicles as these areas should avoid having metal handles come into direct contact with skin as this can create heat and burns. Furthermore, those suffering from heart conditions or having pacemakers should avoid using one as well.

A zapper is simple and requires no special knowledge or soldering to put together, thanks to its use of a 555 timer chip sourced from electronic supply houses at an inexpensive price. For optimal performance, opt for the CMOS version which produces sharper square waves while having lower battery drain.

Construction requires keeping in mind the fact that zappers produce high-frequency square waves – up to 30kHz with 50% duty cycle – so touching it more than briefly during assembly is advised. Furthermore, its positive terminal should be covered with tape in order to prevent shorting out.

Once completed, an oscilloscope should be used to check its functionality prior to use. A specialty electronic shop that services TVs, computers and stereos usually has one available for rental for a few dollars. A multimeter can also be used as an output indicator, though due to tolerance issues with cheap Radio Shack parts it may give inaccurate readings.

People looking to incorporate regular zapping into their bodies should begin with a cleansing regimen a few weeks prior to commencing in order to protect kidneys and liver from becoming overloaded. When assembling their device, protective gloves should also be worn as direct contact may expose users to harmful chemicals or metals such as tin and lead, potentially harmful materials that can be encountered while assembly takes place.

Recommendations

Hulda Clark created the Zapper as part of her controversial practice as an alternative health practitioner. According to Clark, her device could cure many diseases by eliminating parasites and toxins from the body; however, these claims have yet to be validated by rigorous scientific studies or independent investigations; nevertheless, some people report experiencing relief from symptoms associated with certain conditions after using it.

A zapper is a simple electronic device that creates low-voltage pulses of energy from its 9-volt battery to two copper handles or electrodes held or placed anywhere on the body by its user. This frequency of 30kHz may help kill parasites like flukes and roundworms as well as bacteria responsible for contributing to disease.

Clark states that her zapper works by producing frequencies which resonate with the natural frequencies of parasites to destroy them, unlike Rife’s Ray machines which use specific frequencies for each pathogen. Although her device can be used within the home, for optimal results it should be kept outside close to ground-level so as to prevent bugs from flying into it and being vaporized on its wire grid, which could endanger those nearby.

When using a zapper, users should wear protective eyewear and follow all safety instructions. Direct contact between the device and any part of their bodies that conduct electricity (such as eyes or testicles ) should be avoided as well as plugging it into an grounded electrical outlet for optimal use.

Zapping should be performed for at least 45 minutes each session. Some people report feeling a mild heating sensation during treatment while others experience emotional relief due to reduced stress levels. Temporary adverse reactions have also been noted by participants including dizziness or an almost intoxicating feeling.

The SuperZappicator is an advanced variant of zapper that can generate frequencies to kill parasites on surfaces as well as within the digestive tract. Attached directly to skin via alligator clips instead of handholds, this allows it to target larger areas and penetrate deep within bowel.

FAQ

Hulda Clark and her zapper do not boast extensive scientific evidence backing their claims, so it’s wise to consult a health professional if any queries arise before using this device.

Most zappers produce a square wave output consisting of odd harmonics reaching megahertz frequencies that absorb parasites and effectively kill them, while its 50% duty cycle ensures immune stimulation is effective.

The zapper must also be tuned to match each parasite’s frequency (see Dr Clark’s Parasite Frequency book or CAFL frequency book for this purpose). Overuse of zappers may result in killing beneficial gut bacteria, leading to intestinal irregularity; correcting this with foods like yogurt and buttermilk may help.

If you want to go beyond the 30 kHz unit of your zapper, I strongly advise reading Syncrometer Lab Manual and Prevention book by Dr Clark for advanced experiments and uses for your zapper. This book features many advanced experiments not found on her original parts list or within 30 kHz zapper unit.

September 21, 2024|Editorial

Wave Genome Reviews

Wave Pharmaceuticals is developing several RNA editing therapeutics through their PRISM platform to treat disease. One such RNA editing therapeutic for alpha-1 antitrypsin deficiency (AATD), WVE-006, is the first-in-class therapeutic that corrects mutant SERPINA1 Z allele transcript to treat both liver and lung manifestations of this condition.

WAVE proteins are ubiquitously conserved across eukaryotic species, with homologs found in Dictyostelium discoideum and Caenorhabditis elegans. They form part of a heteropentameric complex necessary for remodeling actin cytoskeletons at cell-cell junctions during tissue morphogenesis.

Background

WASPs are a family of proteins with several isoforms, including N-WASP and WAVE1 and 2; their amino-terminal region shares striking similarity with that found in WHD/SHD domain, which has been shown to function as a binding site for activating Arp2/3 complex [25,26]. WAVE complex (Waves Are Vocalic Encoded Complex), found primarily within cell membranes, contains multiple isoforms organized in a heteropentameric complex known as Sra1/CYFIP1 (or PIR121/CYFIP2) subunits as well as Nap1 (Kette in Drosophila), Abi1/2/3 (Abelson-interactors) and HSPC300/Brick1 [26]. These components regulate WAVE complex activity through various mechanisms. GTP-loaded Rac binds to both WAVE2’s proline-rich domain and to IRSp53’s RCB/IMD domain to recruit it to membrane sites [27, 28], while phosphorylation by c-Abl and CK2 reduces WAVE2 activity, thus inhibiting its ability to activate Arp2/3 [26, 27].

WASP and WAVE proteins play a key role in lamellipodial actin formation; in addition, however, they play a critical role in cell adhesion regulation across multicellular organisms. Genetic studies conducted on Dictyostelium discoideum and Caenorhabditis elegans revealed that mutants lacking WAVE homolog wve-1 displayed defects in epidermal cell-cell adhesion as well as intestinal epithelium expansion due to impaired WAVE homolog wve-1 [28]. WASPs contribute by remodelling actin cytoskeleton at cell-cell contacts – an effect also seen during Drosophila wing morphogenesis as well as guidance by striated muscle cells [29, 31].

N-WASP and WAVE1 and 2 genes are highly conserved across species. A TBLAST search on the Ensembl zebrafish genome revealed one N-WASP gene and two each for WAVE1 and 2 (Figure 1). A phylogenetic analysis using this dataset shows that N-WASP, WAVE1, and WAVE2 all originated from an ancestral vertebrate lineage while WAVE2 diverged prior to jawed fish evolution; significant clustering exists among WAVE2 genes suggesting they were recruited specifically onto specific cell types during evolution.

Methods

Wave Life Sciences and GSK plc today announced a strategic collaboration to advance oligonucleotide therapeutics, specifically WVE-006, Wave’s preclinical RNA editing program targeting alpha-1 antitrypsin deficiency (AATD). This partnership offers four years of research time; GSK contributes their vast genetic insights as well as global development capabilities while Wave provides its proprietary drug discovery and drug development platform, PRISM.

Phylogenetic analysis of WASP and WAVE proteins with their highly conserved WH1/EVH1 domains as well as their V/WHD/SHD domains revealed that these two proteins separated into three separate clades during vertebrate evolution (Figure 2). Ancestral WASP and N-WASP were found in jawed fishes and mammals’ common ancestor, suggesting they acquired their unique functions early in vertebrate evolution. These results demonstrate that WAVE1 and possibly WAVE3 had already evolved long before the appearance of jawed vertebrates, supporting the idea that these genes may play a role in neural development in mammals. A phylogenetic tree was created using neighbor-joining methods and ClustalW with bootstrap values greater than 50% displayed.

Results

GSK and Wave have entered into a collaboration and license agreement that will see up to eight programs developed leveraging Wave’s PRISM platform, including WVE-006, an innovative RNA editing therapeutic targeting A-to-I(G) in acute allograft rejection (AATD). Under this deal, Wave expects up to $170 million in upfront payments, development milestone payments and tiered sales royalties over five years.

WASP and WAVE proteins are highly conserved proteins found throughout vertebrates that form a complex with Arp2/3 in cells. Their primary role is cell adhesion; however, they also regulate actin polymerization, membrane dynamics and actin polymerization at cell-cell boundaries [60]. Genetic studies in multicellular organisms demonstrate that WAVE protein is required for epithelial morphogenesis in cultured cells, intestinal epithelial migration in C. elegans embryos as well as muscle formation by remodeling of actin cytoskeleton at cell-cell junctions [61]. Genetic studies of multicellular organisms has demonstrated this requirement [62]. Genetic studies in multicellular organisms has revealed WAVE to be essential in terms of epithelial morphogenesis at cell-cell boundaries [61,62]. Genetic analyses on multicellular organisms indicate WAVE to be required in epithelial morphogenesis during epithelial cell migration at cell boundaries as well as regulation of actin cytoskeleton remodeling at cell junctions [62,63], Drosophila muscle formation [64,65]. Genetic studies show WAVE’s role is required in epithelial cell migration during intestinal epithelial migration; intestinal epithelial migration during C. elegans embryonic migration at cell boundaries as well as Drosophila muscle formation via remodeling the actin cytoskeleton. [65,66]. Studies reveal genetic studies have revealed its dependence for epithelial morphogenesis as epithelial migration which require remodeling at cell-cell boundaries [66]. [68], where remodeling of its actin cytoskeleton remodeling [67]. Genetic studies indicate its requirement in multicellular organisms where WAVE protein requirement needed in C elegans embryo migration of C elegans embryogenesis via C elegans embryo migration as C elegans embryo formation required requiring Drosophilamus cell migration through remodelling] embryo.]. *) that WAVE protein required epitel morphogenesis for epithelial morphogenesis by providing epithelial migration as morphogenesis is required at cell/cell junction remodeling cytoskeleton at cell/cell junction remodeling acts at cell cell/Drosphila. WAVE requirements required epit epit for epit cell migration C elegans embryos embryos embryos requires this requirement as needed when C and Drosian. elegans embryo migration which in C and Drosphila formation which need migration in C/eleg and Drosphila for muscle cell migration C which requires remodeling as needed also requires remodeling of actin morpho formation which requires Remodeling is required also required which. morpho formation within C’s migration within embryo a cell migration also requirements also due ds embryo migration as required remodeling by Drosphila, both WAVE proteins also required WAVE requires remodeling of actin Cy. El elegans embryo embryo elegans embryo embryo. El also required which requires cell migration a for muscle formation which remodeling. elen as required when C for Dross also required cell migration C Cele elen embryo elen embryo.eelsen embryo embryo’s embryo embryo’s embryo’s for Dros. etc e C as required when required remodeling of acts by Drosophila muscle formation needed at cell cultured also C to muscle cell migration required remodeling remodeling due remodelings cell which cell migration C embryo migrate. elen so C by C/legan

Humans possess a WASP gene on chromosome 10 that encodes for a protein of 498 to 559 amino acids (N-WASP and WAVE). Both these genes are transcribed from promoter regions within their genome and this protein phosphorylated and degraded by PP2A according to various signaling pathways triggered by integrins, CDKs, or Rac.

The evolutionary history of WASP and WAVE family members can be discerned through phylogenetic analysis, which reveals that both N-WASP and the homologous human WAVE1 were present in the common ancestor between fish and mammals. WAVE1 and its homologous zebrafish WAVE2 diverged early during vertebrate evolution; thereafter they acquired specific functions in brain development (Figure 2c). Beyond their cytoskeletal functions, these proteins play vital roles in neuronal growth and maturation and the establishment of synaptic connections within nervous systems (Figure 2c).

Conclusions

Wave Life Sciences is a clinical-stage genetic medicines company dedicated to providing life-changing treatments for people suffering from diseases caused by mutations in single genes. Their mission is to discover and develop therapeutics utilizing their proprietary discovery platform PRISM (formerly AIMer). Wave currently has one preclinical oligonucleotide program targeting alpha-1 antitrypsin deficiency called WVE-006, developed jointly with GSK.

Many eukaryotic species contain WASP and WAVE proteins in their genomes. Saccharomyces cerevisiae’s budding yeast Saccharomyces cerevisiae encodes for four WASP/WAVE genes from WSP-1 through WAVE-3 [1] while humans encode for N-WASP to WAVE-3 WASPs via long 490-559 amino-acid genes ranging in length from N-WASP to WAVE-3 (Figure 2a). WAVE2 shares 74% amino acid similarity with its basic domain with that conserved WH1/EVH1 domain of N-WASP; additionally, WAVE2 shares 87% amino acid similarity with that conserved domain of N-WASP while their EVH1 domain of human WAVE2 corresponds exactly with that found on mouse p21/Rac1.

WASPs/WAVEs localize to cell-cell boundaries in cultured epithelial cells of multicellular organisms. This polarization is essential for maintaining integrity of actin cytoskeleton at junctions between cells and for modulating intestinal epithelium expansion during gut colonization.

WAVEs play an essential role in neuron cytoskeletal polarization and upregulation of these proteins can result in cell motility phenotypes associated with various cancers.

Figure 2a presents a phylogenetic tree, created using alignment of conserved EVH1 and WH1/SHD domains of human WASP and WAVE proteins. Ensembl zebrafish genome was also subjected to TBLAST analysis and revealed at least two WASP and three WAVE homologs (see the legend for accession numbers). Furthermore, its phylogenetic tree demonstrated both N-WASP and WAVE as being present in a common ancestor between fish and vertebrates. However, these proteins appear to have diverged early in vertebrate evolution into separate clades of N-WASP and WAVE proteins, possibly in response to jawed fishes possessing adaptive immune systems. Future analysis of the zebrafish genome will be utilized to understand their function in vertebrates.

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