Wave Genetics has demonstrated that all areas of DNA, even its “junk” regions, can be activated or deactivated via resonant waves beamed at it. This has been verified in well-designed and clinically replicated experiments; and can provide life extension and regenerative medicine without using dangerous antiquated methods like recombinant DNA technology or stem cell culture.
Biochemistry
Biochemistry is the study of living matter – cells, organelles and organisms – through scientific examination. As a relatively young science that integrates biology and chemistry to focus on life processes such as protein synthesis, this subdiscipline explores large molecules found in living organisms like proteins, lipids and nucleic acids and how these interact to control or coordinate vital processes within living beings. Biochemistry is commonly known by its alternative names of biological chemistry or molecular biology and has applications across medicine, food production and agriculture sectors.
All forms of life on Earth depend upon biochemical reactions and processes for survival, from energy production through cell respiration to reproduction and development of plants and animals, cell-tissue interactions, and their influence on one another. Therefore biochemistry has become one of the key areas of science with insights gained helping improve medical treatments as well as prevent diseases.
Biochemists often perform laboratory experiments daily using various pieces of equipment, manage research projects, and compose technical reports. Their work may involve extracting live cell samples from plants or animals for genetic testing purposes or performing computational and analytic analysis on data obtained.
Biochemists require more than lab skills; they must also possess excellent communication and organizational abilities in order to work as part of a team environment. Furthermore, they need the ability to think critically and solve problems quickly – this career path makes for an ideal option for individuals interested in working collaboratively as well as analyzing complex information.
Biochemistry is an ever-evolving field, becoming an integral component of many fields of study. For instance, its contributions can be seen in medical research areas like pharmacology, microbiology, pathology and nutrition as well as in forensic science and agriculture. Biochemistry can even be applied in industry with its knowledge making an impactful difference for people around the globe. To succeed in biochemistry it’s essential to have strong mathematical and physics foundations.
Artificial Intelligence
Artificial intelligence – in its computational sense and not the sort that resides in people – has become one of the top hot topics in science today. Some researchers speculate that eventually it may be possible to develop artificial intelligence capable of competing with human brain power; other scientists, however, remain wary that such technology could be misused destructively.
AI can serve a number of beneficial purposes. For instance, researchers can utilize it to quickly identify new drugs by crunching through billions of data points and predict their effects; AI also assists researchers with understanding genetic mutations and their effects; this type of knowledge could prove vital in treating diseases like cancer.
Artificial Intelligence can also be utilized to develop virtual patients to test drug efficacy. These virtual patients can help reduce risks of adverse reactions and enhance treatment outcomes while speeding up development of new medicines. Aside from that application of AI to testing purposes, artificial intelligence also has applications in creating virtual patients that allow us to test drug efficacy before prescribing any actual medicine to real patients. This technique uses various tools including 3D models and computer simulations as a powerful way of creating these ‘virtual patients’ in the medical industry that help develop drugs quickly – an invaluable asset that accelerates drug discovery process greatly.
Deep Genomics of University of Toronto is using artificial intelligence to develop treatments for genetic neuromuscular disorders such as Duchenne muscular dystrophy. Deep Genomics and Wave Life Sciences have formed a partnership in order to discover treatments using Deep Genomics’ machine learning platform and Deep Genomics’ machine-learning platform respectively.
Wave’s Artificial Intelligence research extends into pharmaceutical development as it develops new drugs. Their flagship program, DG12P1, is an oligonucleotide designed to treat Wilson disease; an uncommon, hereditary condition causing copper accumulation in liver and other organs. Wave plans to start clinical trials of this treatment by early 2021.
Wave genetics works on the principle that DNA operates at a wave, or fine-field level. It contains videotapes with instructions to maintain an organism over an indefinitely long period, but over time these instructions become corrupted and errors accumulate, leading to illness or even death. By understanding how these video tapes function it may be possible to renew them and extend a person’s lifespan.
Machine Learning
Machine learning enables the company to analyze large data sets and identify patterns not visible to humans, which allows it to quickly identify potential drug candidates for specific genetic diseases and test these candidates to determine their effectiveness as potential treatments for these conditions. This process forms the cornerstone of developing novel treatments for genetic illnesses.
Wave genetics operates under the premise that DNA video tapes that hold instructions for maintaining health accumulate errors over time (DNA mutations), leading to illness and eventually death. Wave genetics holds that these errors can be corrected; an example being what is referred to as “DNA Phantom Effect”, whereby women who have had sexual intercourse with one man give birth to children with his genetic characteristics.
Gariaev’s team has conducted various experiments based on this theory. One such experiment involved poisoning rats to damage their pancreas, then employing Wave genetics techniques to alter their DNA so that their damaged pancreas would regenerate itself – with astounding results; all rats’ pancreases functioning normally once more after these experiments had concluded.
Neuromuscular Disorders
Neuromuscular disorders result when communication between the brain and nerves breaks down, leading to weakness or atrophy of muscles. While such diseases are typically hereditary, they may also result from abnormal immune reactions or poisoning/injury.
Neuromuscular disease symptoms depend on its cause and can range from muscular weakness, numbness or tingling, difficulty chewing or swallowing, difficulty breathing, spasms and fatigue to progressive conditions that worsen over time. Some forms can even appear prior to birth while others develop later during childhood or adulthood; genetic mutations could play a part; infections, cancer, toxic exposure from drugs or poisoning or inflammation all increase your chances of having one of these issues.
Neuromuscular disorders encompass numerous subcategories, such as muscular dystrophies, amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA), and myopathies. Muscular dystrophies are genetic diseases which damage muscles leading to weakness and degeneration; examples include Duchenne muscular dystrophy, Friedreich’s ataxia, myasthenia gravis. Meanwhile ALS causes gradual muscle weakening leading to difficulty walking or moving, difficulty swallowing food, respiratory issues including sleep disordered breathing among other symptoms.
CNDR’s clinic-based data entry and its partnerships with patient organizations have enabled it to build one of the largest and most comprehensive registries for neuromuscular diseases. These registries can provide the foundation for rigorous real-world evidence clinical outcomes studies for new therapies used to treat these diseases, and represent an essential step toward building a system of care which puts patients first. The CNDR continues to expand activities designed to capture more rigorous longitudinal RWE clinical outcomes for novel therapies being tested in both the United States (e.g., Duchenne Registry) and Canada (Quebec DM Registry). These registries will enable the identification of emerging trends that can help improve healthcare delivery for patients living with these diseases. Furthermore, this data can inform future policy and program developments to maximize available resources.
